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The authors document the cytological features on fine-needle aspiration cytology of a chondroblastoma which appeared as a lytic lesion in the. Chondroblastoma is an uncommon benign cartilage producing neoplasm with a characteristic epiphyseal location. This report documents the. Chondroblastoma is a rare primary bone tumor of young people .. Fine needle aspiration cytology of chondroblastoma of bone. Cancer.

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Case Report An year-old-female presented with pain in left leg for last 1-month and progressively increasing swelling around the knee joint for last 15 days.

Sterling G, Wilson A. Recognition of chondroblasts based on its cytological features has been emphasized as the diagnostic hallmark of this lesion along with chondroid matrix surrounding the individual cells.

Sternberg’s Diagnostic Surgical Pathology. X-ray feature combined with fine-needle aspiration cytology favoured cyto,ogy diagnosis of chondroblastoma, which was further confirmed by histopathological examination. On examination, the patient had restricted left knee joint movements with tenderness.

Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

At cytology, other giant cell-rich tumors and tumorlike lesions such as aneurysmal bone cyst ABCgiant cell tumor, and chondromyxoid fibroma fall under the differential diagnosis of chondroblastoma.

Benign and malignant cartilage tumors of bone and joint: Chondroblastoma of the talus: Plain X-ray showed a well-defined osteolytic lesion involving the right upper fibular epiphysis with a sclerotic rim figure 1.


Fine needle aspiration cytology in the management of tumors and tumor like lesions of bone. Sternberg’s Diagnostic Surgical Pathology.


There is associated cortical destruction with sotissue components. The most common anatomical site involved by this tumour is the proximal humerus followed by the distal femur, proximal femur, proximal tibia, talus and innominate bone, in descending order.

Case Report: Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

Dispersed mononuclear chondroblasts demonstrate well-defined, deeply eosinophilic cytoplasm with centrally or eccentrically placed oval or round nuclei, with longitudinal grooves. Author information Copyright and License information Disclaimer. In correlation with the radiological findings, a provisional diagnosis suggestive of chondroblastoma was chondroblastomw.

Schajowicz F, Gallardo H. Well circumscribed, white – blue – gray, firm Usually 3 – 6 cm Variable calcification, necrosis, cystic areas. This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment.

Tibia and femur were normal [Figure – 1]. Schajowicz F, Gallardo H. Sitemap What’s New Feedback Disclaimer. Fine-needle aspiration FNA is an accurate and rapid technique in establishing the correct diagnosis of osseous neoplasms and it is becoming a valuable preoperative technique in the management of these patients.

Fine needle aspiration cytology of chondroblastoma of the fibula

There was no history of trauma. Case 2 A year-old male presented with diffuse swelling on the shoulder joint of 1-month duration.


Benign cartilaginous tumors almost always appear chonfroblastoma on radiology with sharp circumscribed borders, intact overlying periosteum and no adjacent soft tissue swelling. Another entity to differentiate from chondroblastoma is Langerhan’s cell histiocytosis LCH.

It is usually treated by curettage and bone graft. However, it is unclear whether malignant CMF actually exists or whether it represents another type of sarcoma that has been misdiagnosed. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.

Smears characteristically revealed chondroblasts and osteoclast-like giant cells. One had swelling at the lower end of the femur, whereas in the other case the upper end of the tibia was involved. A review of seventy cases. Plain X-ray showing a well-defined osteolytic lesion involving the right upper fibular epiphysis with a sclerotic rim.

The chondroid and myxoid elements form the irregular fragments of matrix in the background. How to cite chindroblastoma URL: Radiology was not supportive in most of the cases. Areas chondroblasotma increased cell density forming fibrous cap were noted at the periphery of lobules. The intramedullary cyondroblastoma tumors.