tall tropical American timber tree especially abundant in eastern Brazil; yields hard strong durable zebrawood with straight grain and dark strips on a pinkish to . Gonçalo Alves ou Gonçaleiro (Astronium fraxinifolium) Família Anacardiaceae. Árvore rústica de médio porte, comum em várias regiões, ás vezes chamada de. PDF | Essential oils produced from leaves of Astronium fraxinifolium Schott. harvested at four different stages of maturity have been analyzed by GC/MS.
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Astronium fraxinifolium Images – Useful Tropical Plants
Cytotoxicity of the plant material. Leishmaniasis is a disease that affects human beings and animals and is astronimu by the protozoa parasite of the genus Leishmania which is transmitted by the bite of infected female phlebotomine sandflies and displays a spectrum of manifestations which goes from cutaneous involvement CL with late destruction of mucous membranes to generalized systemic visceral disease VL with fatal outcome if not treated [ 1 ].
The parasites were fixed in formaldehyde, stained with Trypan blue and visualized at light microscope at x magnification.
Furthermore, the continuous use of ineffective drugs has led to the development of resistance to their compounds [ 16 ], which have stirred an urgent need for novel, effective, and safe drugs for treatment of leishmaniasis. The essential oil of P. If you would like to support this site, please consider Donating.
Subscribe to Table of Contents Alerts. Introduction Leishmaniasis is a disease that affects human beings and animals and is caused by the protozoa parasite of the genus Leishmania which is transmitted by the bite of infected female phlebotomine sandflies and displays a spectrum of manifestations which fraxinkfolium from cutaneous involvement CL with late destruction of mucous membranes to generalized systemic visceral disease VL with fatal outcome if not treated [ 1 ].
Table of Contents Alerts. HIV-positive individuals are probably at high risk of developing cutaneous leishmaniasis [ 9 ] probably at more severe forms of the disease. Another problem is related to fraxihifolium lower efficacy of the drugs in children compared to adults [ 11 ]. Last update on Several fraxinifloium have been published confirming much of the popular use of Plectranthus amboinicussuch as anti-inflammatory and antimicrobial activities [ 23 — 27 ].
The animals were injected subcutaneously in the right hind footpad with 10 6 stationary phase L. Probably the essential oil of P. The animals showed a significant reduction of lesion thickness in the 6th week, but it was not comparable to the animals treated with Glucantime.
Astronium fraxinifolium Schott Anacardiaceae Some works treat this species as a form or just a synonym of Astronium graveolens. Results and Discussion In the present study we decided to evaluate two medicinal plants, Plectranthus amboinicus and Astronium fraxinifolium.
This fact could be related to the concentration of the essential oil, to the route of administration, or even fraxinifolum the period of treatment. The ethanolic extracts of the bark, sapwood, and leaves of A.
Publisher Reference Publications; Michigan. Treatment was fraxinfolium by administering OEPA intralesionally i.
Further, golden hamsters were infected s. One hundred microliters of these dilutions was distributed into well flat bottom plates containing agar-blood in 6 replicates per concentration. Carvacrol is a monoterpene phenol, isomer to thymol, and presents various biological activities such as antimicrobial, antitumor, and anti-inflammatory activities [ 32 ].
Tropical Plants Database, Ken Fern. Lesion thickness of hamster footpad infected with 10 6 promastigotes of Leishmania braziliensis. The animals were injected subcutaneously in right hind footpad with 10 7 stationary phase L. Treatment with Ethanolic Extracts of Leaves from A. View at Google Scholar F.
Goncalo alves Astronium fraxinifolium
Despite the promising in vitro results, in vivo experiments did not reveal a good efficacy of the treatment with EOPA in mouse model. For the in vitro tests, essential oil of P. The parasites were counted in a Neubauer chamber. Several studies have been done ashronium order to evaluate antileishmanicidal activity of medicinal plants [ 1718 ].
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The profiles of lesion thickness were similar to the standard treatment. View at Google Scholar P. However, a higher number of parasites were found when the group of animals treated with the plant material was compared with the group treated with Glucantime. Statistical Analysis The data relating to the parasite load were analyzed using the nonparametric Mann-Whitney test.
According to the World of Health Organization [ 2 ], about 0. Indexed in Science Citation Index Expanded. Astronium fraxinifolium is original from the central-west region of Brazil, but it has also been found in various regions of the northeastern region of the country.
The astrpnium of the present work was to evaluate antileishmanial activity of Astronium fraxinifolium and Plectranthus amboinicus. Lesion sizes were measured weekly with a dial gauge caliper 0. The lesion sizes from treated and untreated animals were analysed by the one-way Anova and complemented by the Tukey-Kramer test for multiple comparisons.
Leishmania amazonensisand L. Year ISBN Description An extremely concise book, listing approximately 1, species and varieties of plants with their botanical name, common name in Brazil, regions in Brazil where the plant is found, a brief list of uses and any medically active compounds in the plant.
The Myracrodruon aztronium species, a plant of the same family, native in northeastern Brazil, is widely used in folk medicine for treatment of various dermatological disorders and is known to have antimicrobial [ 19 ], antiulcer [ 20 ], and anti-inflammatory activities [ 21 ]. The supernatant was discarded, and the cells were resuspended in culture medium.
A superb work, with the minor irritation that the translation from Portuguese is not of the best. Any loss of weight was not observed in the animals treated with the plant material. No difference was found when the animals treated with the plant material and the untreated animals were compared in terms of lesion thickness Figure 3.
Nonetheless, we decided to test the EOPA treatment in animal models based on data from other researchers [ 33 ] who showed a good antileishmanial activity of essential oil, in the case of Lippia sidoides Cham.
Antileishmanial Evaluation The in vitro evaluation of the antileishmanial activity of the essential oil from P.